Single-stranded DNA repeat synthesis by telomerase
نویسندگان
چکیده
منابع مشابه
Single-stranded DNA repeat synthesis by telomerase.
The eukaryotic ribonucleoprotein reverse transcriptase (RT) telomerase uses a template within its integral RNA subunit to extend chromosome ends by synthesis of single-stranded telomeric repeats. Telomerase is adapted to its unique cellular role by an ability to release product DNA in single-stranded form, regenerating free template from the product-template hybrid. Furthermore, by retaining a ...
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ژورنال
عنوان ژورنال: Current Opinion in Chemical Biology
سال: 2011
ISSN: 1367-5931
DOI: 10.1016/j.cbpa.2011.07.011